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WHO Certifies GPO Facility for Efavirenz Production, Enhancing Access to HIV Treatment
WHO Prequalification for GPO’s Efavirenz Production
The World Health Organization (WHO) has officially certified the Government Pharmaceutical Organization’s (GPO) facility in Pathum Thani under the WHO Prequalification Programme (WHO PQ) for the production of the antiretroviral drug Efavirenz. This certification marks a significant milestone as it is the first of its kind in Thailand and the ASEAN region.
Importance of WHO Certification for Efavirenz
GPO director Mingkwan Suphanpong stated that this certification ensures that Efavirenz tablets manufactured by the GPO remain on the WHO Prequalified List. The WHO had previously approved GPO’s request to include Efavirenz on its list in 2018, following an application submitted in 2016.
Role of Efavirenz in HIV Treatment
Efavirenz is a critical medication prescribed to all individuals diagnosed with HIV. It is commonly used in combination with tenofovir/emtricitabine for adults, adolescents, and children. Additionally, it plays a role in post-exposure prophylaxis regimens to reduce the risk of HIV infection among those exposed to significant risk.
Commitment to Quality and Safety
Dr. Mingkwan emphasized that this certification reflects GPO’s dedication to quality and safety, ensuring that Thai citizens have access to effective medications comparable to original formulations. The certification also opens doors for GPO to register the drug in other countries, enhancing export opportunities.
Compliance with WHO Standards
The certification followed a rigorous inspection conducted from August 12-16 last year, assessing compliance with WHO standards regarding manufacturing processes, production support systems, laboratory practices, and quality management. This certification is valid for three years.
Advancements in Generic Drug Production
Dr. Mingkwan highlighted that GPO’s success in producing Efavirenz exemplifies its capabilities in developing generic drugs, particularly essential medicines vital for the healthcare system. Generic medications provide affordable treatment options for Thais while maintaining international credibility.
Future Directions for GPO
To continue benefiting patients after original drug patents expire, Dr. Mingkwan stressed the importance of ongoing research and development of generic drugs by GPO. This proactive approach ensures immediate access to affordable alternatives once patents lapse.
Enhancing Quality of Life for HIV Patients
The recent success of GPO also contributes to improving the quality of life for HIV patients, allowing them to live normal lives akin to non-HIV individuals. According to WHO guidelines, individuals living with HIV who maintain an undetectable viral load pose no risk of transmitting the virus to others.
Advocacy for PLHIV Rights
Jarunee Siriphan, director of the Foundation for Action on Inclusion Rights (Fair), emphasized the significance of the “undetectable equals untransmittable” (U=U) campaign. This public health initiative empowers people living with HIV (PLHIV) by promoting their health and potential without stigma.
Call for Public Health Integration
While acknowledging WHO’s stance on U=U, Jarunee urged the Public Health Ministry to officially certify this approach and integrate it into public policy. She cautioned against employers exploiting this concept by demanding proof of viral suppression during recruitment processes, which could violate individual rights.
A Step Forward in HIV Treatment Accessibility
The WHO certification of GPO’s facility represents a pivotal advancement in Thailand’s efforts to enhance access to effective HIV treatments. By fostering an environment that supports both medical innovation and patient rights, Thailand is making strides towards a healthier future for all individuals living with HIV.
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Liverpool Prioritize Contract Renewals Over New Signings in January
First January deal confirmed as Virgil van Dijk speaks out on contracts
Liverpool are trying to tie down Mohamed Salah, Virgil van Dijk and Trent Alexander-Arnold to new contracts during the January transfer window and have confirmed their first deal of the month
Liverpool have a clear priority in the January transfer window – and it is very different to some of their Premier League rivals.
While some of their closest rivals need to strengthen their squads by bringing in new players, the Reds are focused on keeping what they already have. That means getting new contracts signed for Mohamed Salah, Virgil van Dijk and Trent Alexander-Arnold.
The star trio’s current deals expire at the end of June and they are therefore allowed to speak with foreign clubs about the possibility of a free transfer in the summer. That isn’t an issue for Salah and Van Dijk, who are now expected to sign two-year extensions, but Alexander-Arnold is being courted by Real Madrid.
Liverpool have rejected a first £20million offer for the 26-year-old, but the ball is now in his court. In the meantime, there are plenty of other stories to look at involving transfers and the club.
Liverpool confirmed on Monday that young goalkeeper Marcelo Pitaluga has moved back to Fluminense on a permanent deal. The 22-year-old joined Liverpool for £1.8m in 2020 but never made a first-team appearance, having spent time on loan with Macclesfield, St Patrick’s Athletic and Livingston.
With Alisson Becker and Caoimhin Kelleher ahead of him in the pecking order, the closest he came to the Liverpool first team was being named in seven match day squads.
The club said in a statement: “Everyone at LFC wishes Marcelo the best of luck for the future.” Although he’s left on a free transfer, Liverpool reportedly have a 40 per cent sell-on clause with Pitaluga, meaning they could be due money in the future.
Liverpool want to keep Mohamed Salah, Virgil van Dijk and Trent Alexander-Arnold ( Image: Liverpool FC via Getty Images202)
Captain Virgil van Dijk is expected to pen a new contract with Liverpool, but speaking after Sunday’s 2-2 draw against Manchester United, he revealed that confirmation of him staying is no closer.
Speaking to Sky Sports, he said: “I don’t think so, but I am calm about it, like I said months ago. We’ll see what happens in the future and at this point I have got absolutely no update. It’s all about at the moment focusing, for me and the team, on Spurs [on Wednesday night]. It will be a tough game again, but a good [Carabao Cup] semi-final.”
He also spoke about the Alexander-Arnold situation, saying: “I am fine with it. Trent has his own people around him, his family and we are there as well. He wants to perform in the best way possible like we all do. That is the main focus. In my opinion, maybe ask him, that is the distraction… the game.”
Federico Chiesa’s agent has confirmed that the Italian winger will stay with Liverpool this season despite links with Napoli. Chiesa has made just four appearances for Liverpool since joining the club for £10m plus a further £2.5m in add-ons from Juventus in August.Liverpool’s approach to the January transfer window stands apart from their Premier League rivals. While many teams are focused on reinforcing their squads with new signings, the Reds are concentrating on securing the futures of key players already at the club. The club’s primary goal this month is to finalize new contracts for Mohamed Salah, Virgil van Dijk, and Trent Alexander-Arnold.
Retaining the Core Trio
The contracts for Salah, Van Dijk, and Alexander-Arnold are set to expire in June. This situation permits them to negotiate pre-contract agreements with foreign clubs for a potential free transfer in the summer. However, Liverpool is working diligently to prevent such scenarios. Salah and Van Dijk are reportedly close to agreeing on two-year extensions, while Alexander-Arnold’s future remains less certain due to interest from Real Madrid.
Real Madrid has already made a £20 million offer for the 26-year-old full-back, which Liverpool promptly rejected. The decision now rests with Alexander-Arnold as the club hopes to secure his commitment amidst external interest.
Young Talent Moves On
In a confirmed January move, Liverpool announced that young goalkeeper Marcelo Pitaluga has permanently transferred to Fluminense. The 22-year-old joined Liverpool in 2020 for £1.8 million but failed to make a first-team appearance. During his time with the club, he went on loan spells with Macclesfield, St Patrick’s Athletic, and Livingston. Despite leaving on a free transfer, Liverpool included a 40% sell-on clause in the deal, potentially benefiting from future transactions involving the player.
A club statement read, “Everyone at LFC wishes Marcelo the best of luck for the future.” Pitaluga’s departure reflects the depth in Liverpool’s goalkeeping department, with Alisson Becker and Caoimhin Kelleher firmly ahead in the pecking order.
Van Dijk and Team Dynamics
Team captain Virgil van Dijk remains a pivotal figure at Anfield, and his contract renewal is highly anticipated. Following Liverpool’s 2-2 draw with Manchester United, Van Dijk addressed his contract situation, stating to Sky Sports, “I don’t think so, but I am calm about it, like I said months ago. We’ll see what happens in the future. Right now, my focus is on the team and our upcoming game against Spurs in the Carabao Cup semi-final.”
Van Dijk also weighed in on Alexander-Arnold’s contract situation, expressing confidence in the player’s professionalism. “Trent has his own people around him, his family, and we are here to support him. His main focus is on performing at his best, and that’s all that matters right now,” he said.
Federico Chiesa Staying Put
Meanwhile, rumors surrounding Federico Chiesa’s future have been quashed. Despite links to Serie A clubs Napoli, Roma, and Fiorentina, Chiesa’s agent, Vali Ramadan, confirmed the Italian winger’s commitment to Liverpool. “Napoli did not negotiate a contract with Chiesa from Liverpool in the winter period, and the club has no intention of dispensing with the player. He is continuing with Liverpool and looking forward to more opportunities in the coming months,” Ramadan stated.
Chiesa, who joined Liverpool from Juventus in August for £10 million plus £2.5 million in add-ons, has made just four appearances so far. The club sees him as a valuable asset for the future and intends to integrate him further into the squad.
Conclusion
Liverpool’s strategy this January revolves around stability and retention. By prioritizing contract renewals for key players like Salah, Van Dijk, and Alexander-Arnold, the club aims to build on its current strengths while maintaining a cohesive squad. With young talents like Pitaluga moving on and players like Chiesa committed to staying, Liverpool is laying the groundwork for sustained success.
He has been linked with a move back to Italy, with Napoli, Roma and his former club Fiorentina said to be interested. But his agent Vali Ramadan has rubbished those reports.
“Napoli did not negotiate a contract with Chiesa from Liverpool in the winter period, and the club has no intention of dispensing with the player,” he told 365scores. “The player is continuing with Liverpool and is seeking the opportunity to participate in the coming period. This is what I can confirm now.”
News
Thailand Post Announces Postage Fee Increases Amid Rising Operational Costs
Thailand Post Implements Second Rate Hike in Three Years
Thailand Post has officially announced the second phase of service charge increases, following a previous hike in 2022. This adjustment comes as the state enterprise grapples with rising operational costs that have impacted its financial sustainability.
Historical Context of Rate Adjustments
The 2022 rate changes marked the first increase in over 18 years, reflecting the significant economic pressures faced by the organization. The new rates will apply to a variety of services, including envelope letters, packaged letters, registered envelope letters, printed goods, postcards, and parcels.
Encouragement to Use Eco Post Service
In light of the new pricing structure, Thailand Post has encouraged customers to consider using the Eco Post service as a more economical alternative to registered mail. Eco Post provides a cost-effective option while still allowing customers to track their shipments effectively.
Navigating Economic Challenges
As Thailand Post adjusts its service fees, it highlights the ongoing challenges within the postal industry amid rising costs and evolving market demands. Customers are urged to stay informed about these changes and explore alternative services that may better suit their needs during this transition.
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Chevron Thailand Donates 666,000 Baht for Southern Thailand Flood Relief Efforts
Chevron’s Generous Contribution to Flood Relief
Chevron Thailand Exploration and Production, Ltd. has made a significant donation of 666,806 baht to the Thai Red Cross Society to support flood relief efforts in southern Thailand. The donation was presented by Pornsuree Konanta, Vice President of Corporate Affairs, and received by Janprapa Vichitcholchai, Deputy Director of the Fund-Raising Bureau.
Impact of Severe Flooding in Southern Thailand
The southern region of Thailand has been severely affected by heavy rainfall since November 2024, particularly in provinces such as Nakhon Si Thammarat, Phatthalung, Satun, Pattani, Yala, and Narathiwat. This contribution aims to aid communities that have experienced significant hardships due to flooding.
Part of the “Chevron Humankind” Initiative
This donation is part of Chevron’s decade-long initiative known as “Chevron Humankind,” which encourages employees to engage in charitable activities. Under this program, Chevron matches employee donations twofold. This year, the company matched employee contributions to the Thai Red Cross Society, resulting in a total donation of 666,806 baht dedicated to assisting flood-affected areas.
Previous Contributions to Support Local Communities
In December 2024, Chevron also donated 100,000 baht to the Nakhon Si Thammarat Journalists Association. This funding supports the Pracha Ruamchai Foundation’s mission to provide essential food and drinking water to flood victims in Nakhon Si Thammarat, ensuring that urgent assistance reaches those in need.
Commitment to Corporate Social Responsibility
Chevron’s proactive approach highlights its commitment to corporate social responsibility and community support during times of crisis. By providing financial assistance and encouraging employee involvement in charitable efforts, Chevron demonstrates its dedication to making a positive impact on the lives of those affected by natural disasters in southern Thailand.
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